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| Game | Home | Line | Pts | Adj Pts | Visitor | Line | Pts | Adj Pts | Winner | Picked | Home | Visitor |
| 1 | Michigan State (MSU) | 4 | 31 | 27.0 | Michigan (MIC) | 34 | 34.0 | Michigan (MIC) | 35 | 28 | 7 | |
| 2 | Missouri (MIZ) | 20 | 20.0 | Texas (TEX) | 14.5 | 51 | 36.5 | Texas (TEX) | 20 | 5 | 15 | |
| 3 | Wisconsin (WIS) | 18.5 | 41 | 22.5 | Indiana (IND) | 24 | 24.0 | Indiana (IND) | 11 | 8 | 3 | |
| 4 | Iowa (IOW) | 17.5 | 35 | 17.5 | Illinois (ILL) | 7 | 7.0 | Iowa (IOW) | 6 | 5 | 1 | |
| 5 | Louisville (LOU) | 37.5 | 61 | 23.5 | Florida International (FIU) | 10 | 10.0 | Louisville (LOU) | 5 | 2 | 3 | |
| 6 | Maryland (MRY) | 45 | 45.0 | Virginia (VIR) | 3.5 | 33 | 29.5 | Maryland (MRY) | 12 | 1 | 11 | |
| 7 | West Virginia (WVU) | 17 | 17.0 | Virginia Tech (VTK) | 11 | 34 | 23.0 | Virginia Tech (VTK) | 15 | 4 | 11 | |
| 8 | Army (ARM) | 13 | 13.0 | Connecticut (CON) | 10 | 47 | 37.0 | Connecticut (CON) | 5 | 1 | 4 | |
| 9 | Texas A&M (ATM) | 23.5 | 16 | -7.5 | Baylor (BAY) | 13 | 13.0 | Baylor (BAY) | 10 | 9 | 1 | |
| 10 | North Carolina (NCU) | 3.5 | 31 | 27.5 | Utah (UTA) | 17 | 17.0 | North Carolina (NCU) | 5 | 4 | 1 | |
| 11 | Duke (DUK) | 21 | 21.0 | Navy (NAV) | 6 | 28 | 22.0 | Navy (NAV) | 7 | 0 | 7 | |
| 12 | Boston College (BOS) | 34.5 | 38 | 3.5 | Ball State (BAL) | 0 | 0.0 | Boston College (BOS) | 4 | 4 | 0 | |
| 13 | Oklahoma State (OKS) | 0 | 0.0 | Colorado (COL) | 3.5 | 34 | 30.5 | Colorado (COL) | 6 | 0 | 6 | |
| 14 | Eastern Michigan (EMU) | 3 | 27 | 24.0 | Kent State (KNT) | 20 | 20.0 | Eastern Michigan (EMU) | 1 | 1 | 0 | |
| 15 | Wyoming (WYO) | 16 | 42 | 26.0 | UNLV (UNL) | 17 | 17.0 | Wyoming (WYO) | 5 | 4 | 1 | |
| 16 | Florida State (FSU) | 21 | 38 | 17.0 | Syracuse (SYR) | 14 | 14.0 | Florida State (FSU) | 3 | 2 | 1 | |
| 17 | Arizona State (ASU) | 28 | 28.0 | USC (USC) | 17 | 38 | 21.0 | Arizona State (ASU) | 22 | 5 | 17 | |
| 18 | Alabama (ALA) | 3.5 | 31 | 27.5 | Florida (FLA) | 3 | 3.0 | Alabama (ALA) | 17 | 4 | 13 | |
| 19 | Wake Forest (WFU) | 31 | 31.0 | Clemson (CLE) | 6.5 | 27 | 20.5 | Wake Forest (WFU) | 7 | 0 | 7 | |
| 20 | Penn State (PSU) | 44 | 44.0 | Minnesota (MIN) | 2.5 | 14 | 11.5 | Penn State (PSU) | 14 | 3 | 11 | |
| 21 | Nebraska (NEB) | 3.5 | 27 | 23.5 | Iowa State (ISU) | 20 | 20.0 | Nebraska (NEB) | 13 | 3 | 10 | |
| 22 | Oregon State (ORS) | 2 | 44 | 42.0 | Washington State (WSU) | 33 | 33.0 | Oregon State (ORS) | 6 | 4 | 2 | |
| 23 | Bowling Green (BGU) | 28 | 70 | 42.0 | Temple (TEM) | 7 | 7.0 | Bowling Green (BGU) | 6 | 5 | 1 | |
| 24 | Marshall (MAR) | 11.5 | 16 | 4.5 | SMU (SMU) | 13 | 13.0 | SMU (SMU) | 2 | 2 | 0 | |
| 25 | Idaho (IDA) | 27 | 27.0 | Utah State (UST) | 3 | 13 | 10.0 | Idaho (IDA) | 3 | 0 | 3 | |
| 26 | Akron (AKR) | 10.5 | 17 | 6.5 | Central Michigan (CMU) | 31 | 31.0 | Central Michigan (CMU) | 0 | 0 | 0 | |
| 27 | UAB (UAB) | 17.5 | 45 | 27.5 | Rice (RCE) | 26 | 26.0 | UAB (UAB) | 2 | 0 | 2 | |
| 28 | East Carolina (ECU) | 7 | 7.0 | Southern Miss (SOM) | 7 | 33 | 26.0 | Southern Miss (SOM) | 2 | 1 | 1 | |
| 29 | California (CAL) | 16 | 28 | 12.0 | Arizona (ARZ) | 0 | 0.0 | California (CAL) | 15 | 12 | 3 | |
| 30 | Auburn (AUB) | 11.5 | 48 | 36.5 | South Carolina (SCL) | 7 | 7.0 | Auburn (AUB) | 7 | 6 | 1 | |
| 31 | Oklahoma (OKA) | 6.5 | 43 | 36.5 | Kansas State (KSU) | 21 | 21.0 | Oklahoma (OKA) | 8 | 5 | 3 | |
| 32 | Vanderbilt (VAN) | 16.5 | 15 | -1.5 | Middle Tenn. St. (MTS) | 17 | 17.0 | Middle Tenn. St. (MTS) | 1 | 1 | 0 | |
| 33 | Louisiana Tech (LTK) | 10 | 34 | 24.0 | New Mexico State (NMS) | 14 | 14.0 | Louisiana Tech (LTK) | 1 | 0 | 1 | |
| 34 | Louisiana Monroe (LAM) | 31 | 31.0 | Arkansas State (ARS) | 1 | 27 | 26.0 | Louisiana Monroe (LAM) | 1 | 0 | 1 | |
| 35 | TCU (TCU) | 2.5 | 49 | 46.5 | New Mexico (NMU) | 28 | 28.0 | TCU (TCU) | 5 | 3 | 2 | |
| 36 | Tulsa (TLS) | 3 | 23 | 20.0 | Houston (HOU) | 30 | 30.0 | Houston (HOU) | 3 | 2 | 1 | |
| 37 | Texas Tech (TEK) | 16.5 | 30 | 13.5 | Kansas (KAN) | 17 | 17.0 | Kansas (KAN) | 11 | 11 | 0 | |
| 38 | San Jose State (SJS) | 23 | 23.0 | Nevada (NEV) | 4 | 30 | 26.0 | Nevada (NEV) | 0 | 0 | 0 | |
| 39 | Purdue (PUR) | 2.5 | 28 | 25.5 | Notre Dame (NDM) | 49 | 49.0 | Notre Dame (NDM) | 19 | 4 | 15 | |
| 40 | Miami Fla (MIF) | 20.5 | 27 | 6.5 | South Florida (SFL) | 7 | 7.0 | South Florida (SFL) | 8 | 6 | 2 | |
| 41 | La Lafayette (LAL) | 21 | 21.0 | Central Florida (CFL) | 3.5 | 24 | 20.5 | La Lafayette (LAL) | 3 | 0 | 3 | |
| 42 | Memphis (MEM) | 27 | 27.0 | UTEP (UTP) | 3 | 20 | 17.0 | Memphis (MEM) | 4 | 0 | 4 | |
| 43 | San Diego State (SDS) | 31 | 31.0 | BYU (BYU) | 2 | 10 | 8.0 | San Diego State (SDS) | 1 | 1 | 0 | |
| 44 | UCLA (UCL) | 21 | 21 | 0.0 | Washington (WAS) | 17 | 17.0 | Washington (WAS) | 12 | 11 | 1 | |
| 45 | Hawaii (HAW) | 41 | 41.0 | Boise State (BSU) | 10.5 | 44 | 33.5 | Hawaii (HAW) | 7 | 1 | 6 |