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| Game | Home | Line | Pts | Adj Pts | Visitor | Line | Pts | Adj Pts | Winner | Picked | Home | Visitor |
| 1 | Clemson (CLE) | 25 | 25.0 | Texas A&M (ATM) | 1.5 | 24 | 22.5 | Clemson (CLE) | 42 | 9 | 33 | |
| 2 | Michigan State (MSU) | 19.0 | 49 | 30.0 | Kent State (KNT) | 14 | 14.0 | Michigan State (MSU) | 11 | 10 | 1 | |
| 3 | Ohio State (OSU) | 14.0 | 34 | 20.0 | Miami Ohio (MIO) | 14 | 14.0 | Ohio State (OSU) | 18 | 16 | 2 | |
| 4 | Northwestern (NWS) | 14.5 | 38 | 23.5 | Ohio (OHU) | 14 | 14.0 | Northwestern (NWS) | 4 | 3 | 1 | |
| 5 | Illinois (ILL) | 1.5 | 33 | 31.5 | Rutgers (RUT) | 30 | 30.0 | Illinois (ILL) | 20 | 19 | 1 | |
| 6 | Arkansas State (ARS) | 25.5 | 17 | -8.5 | Missouri (MIZ) | 44 | 44.0 | Missouri (MIZ) | 15 | 1 | 14 | |
| 7 | Oklahoma (OKA) | 26.0 | 10 | -16.0 | TCU (TCU) | 17 | 17.0 | TCU (TCU) | 14 | 9 | 5 | |
| 8 | Wisconsin (WIS) | 3.5 | 56 | 52.5 | Bowling Green (BGU) | 42 | 42.0 | Wisconsin (WIS) | 20 | 14 | 6 | |
| 9 | Iowa (IOW) | 38.5 | 56 | 17.5 | Ball State (BAL) | 0 | 0.0 | Iowa (IOW) | 12 | 6 | 6 | |
| 10 | Tennessee (TEN) | 23.5 | 17 | -6.5 | UAB (UAB) | 10 | 10.0 | UAB (UAB) | 17 | 14 | 3 | |
| 11 | East Carolina (ECU) | 24 | 24.0 | Duke (DUK) | 2.0 | 21 | 19.0 | East Carolina (ECU) | 7 | 5 | 2 | |
| 12 | Kansas State (KSU) | 33.0 | 35 | 2.0 | Florida International (FIU) | 21 | 21.0 | Florida International (FIU) | 9 | 8 | 1 | |
| 13 | BYU (BYU) | 3 | 3.0 | Boston College (BOS) | 3.5 | 20 | 16.5 | Boston College (BOS) | 14 | 6 | 8 | |
| 14 | Michigan (MIC) | 18.5 | 33 | 14.5 | Northern Illinois (NIL) | 17 | 17.0 | Northern Illinois (NIL) | 20 | 18 | 2 | |
| 15 | Air Force (AIR) | 20 | 20.0 | Washington (WAS) | 2.5 | 17 | 14.5 | Air Force (AIR) | 12 | 7 | 5 | |
| 16 | Penn State (PSU) | 23.0 | 23 | 0.0 | South Florida (SFL) | 13 | 13.0 | South Florida (SFL) | 13 | 2 | 11 | |
| 17 | Colorado (COL) | 7.5 | 31 | 23.5 | Colorado State (CSU) | 28 | 28.0 | Colorado State (CSU) | 9 | 3 | 6 | |
| 18 | Georgia (GEO) | 7.5 | 48 | 40.5 | Boise State (BSU) | 13 | 13.0 | Georgia (GEO) | 13 | 10 | 3 | |
| 19 | Florida (FLA) | 22.0 | 32 | 10.0 | Wyoming (WYO) | 14 | 14.0 | Wyoming (WYO) | 17 | 10 | 7 | |
| 20 | Navy (NAV) | 8.0 | 20 | 12.0 | Maryland (MRY) | 23 | 23.0 | Maryland (MRY) | 15 | 0 | 15 | |
| 21 | Virginia (VIR) | 33.0 | 31 | -2.0 | Western Michigan (WMU) | 19 | 19.0 | Western Michigan (WMU) | 4 | 3 | 1 | |
| 22 | Kansas (KAN) | 23.0 | 30 | 7.0 | Florida Atlantic(FAU) | 19 | 19.0 | Florida Atlantic(FAU) | 9 | 8 | 1 | |
| 23 | Hawaii (HAW) | 17 | 17.0 | USC (USC) | 34.0 | 63 | 29.0 | USC (USC) | 18 | 9 | 9 | |
| 24 | Alabama (ALA) | 22.0 | 26 | 4.0 | Middle Tenn. St. (MTS) | 7 | 7.0 | Middle Tenn. St. (MTS) | 3 | 2 | 1 | |
| 25 | Texas (TEX) | 39.5 | 60 | 20.5 | La Lafayette (LAL) | 3 | 3.0 | Texas (TEX) | 7 | 7 | 0 | |
| 26 | SMU (SMU) | 23 | 23.0 | Baylor (BAY) | 2.5 | 28 | 25.5 | Baylor (BAY) | 11 | 2 | 9 | |
| 27 | LSU (LSU) | 33.0 | 33 | 0.0 | North Texas (NTX) | 0 | 0.0 | -1 | 7 | 4 | 3 | |
| 28 | Pittsburgh (PIT) | 3.5 | 21 | 17.5 | Notre Dame (NDM) | 42 | 42.0 | Notre Dame (NDM) | 21 | 10 | 11 | |
| 29 | Auburn (AUB) | 7.0 | 14 | 7.0 | Georgia Tech (GTK) | 23 | 23.0 | Georgia Tech (GTK) | 12 | 9 | 3 | |
| 30 | San Diego State (SDS) | 21 | 21.0 | UCLA (UCL) | 7.5 | 44 | 36.5 | UCLA (UCL) | 17 | 2 | 15 | |
| 31 | New Mexico State (NMS) | 17 | 17.0 | UTEP (UTP) | 10.5 | 34 | 23.5 | UTEP (UTP) | 10 | 2 | 8 |