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| Game | Home | Line | Pts | Adj Pts | Visitor | Line | Pts | Adj Pts | Winner | Picked | Home | Visitor |
| 1 | Texas Tech (TEK) | 17 | 56 | 39.0 | Texas A&M (ATM) | 17 | 17.0 | Texas Tech (TEK) | 34 | 22 | 12 | |
| 2 | Northwestern (NWS) | 28 | 28.0 | Iowa (IOW) | 2.5 | 27 | 24.5 | Northwestern (NWS) | 8 | 7 | 1 | |
| 3 | Indiana (IND) | 21 | 21.0 | Minnesota (MIN) | 13 | 42 | 29.0 | Minnesota (MIN) | 13 | 3 | 10 | |
| 4 | Purdue (PUR) | 28 | 28.0 | Michigan State (MSU) | 5.5 | 21 | 15.5 | Purdue (PUR) | 15 | 1 | 14 | |
| 5 | North Carolina (NCU) | 16 | 16.0 | Boston College (BOS) | 4.5 | 14 | 9.5 | North Carolina (NCU) | 13 | 1 | 12 | |
| 6 | Rutgers (RUT) | 3 | 31 | 28.0 | South Florida (SFL) | 45 | 45.0 | South Florida (SFL) | 10 | 9 | 1 | |
| 7 | Baylor (BAY) | 0 | 0.0 | Texas (TEX) | 28 | 62 | 34.0 | Texas (TEX) | 15 | 4 | 11 | |
| 8 | Kansas (KAN) | 40 | 40.0 | Nebraska (NEB) | 1 | 15 | 14.0 | Kansas (KAN) | 18 | 5 | 13 | |
| 9 | Kentucky (KEN) | 27 | 27.0 | Auburn (AUB) | 22.5 | 49 | 26.5 | Kentucky (KEN) | 6 | 3 | 3 | |
| 10 | Clemson (CLE) | 31 | 49 | 18.0 | Duke (DUK) | 20 | 20.0 | Duke (DUK) | 7 | 3 | 4 | |
| 11 | Central Michigan (CMU) | 28 | 28.0 | Northern Illinois (NIL) | 3 | 31 | 28.0 | -1 | 6 | 2 | 4 | |
| 12 | Eastern Michigan (EMU) | 36 | 36.0 | Western Michigan (WMU) | 4.5 | 44 | 39.5 | Western Michigan (WMU) | 7 | 2 | 5 | |
| 13 | Georgia Tech (GTK) | 7.5 | 30 | 22.5 | Wake Forest (WFU) | 17 | 17.0 | Georgia Tech (GTK) | 2 | 2 | 0 | |
| 14 | Navy (NAV) | 12.5 | 49 | 36.5 | Tulane (TUL) | 21 | 21.0 | Navy (NAV) | 0 | 0 | 0 | |
| 15 | Ball State (BAL) | 23 | 23.0 | Akron (AKR) | 2 | 17 | 15.0 | Ball State (BAL) | 5 | 2 | 3 | |
| 16 | Miami Ohio (MIO) | 27.5 | 54 | 26.5 | Buffalo (BUF) | 13 | 13.0 | Miami Ohio (MIO) | 1 | 0 | 1 | |
| 17 | Iowa State (ISU) | 7.5 | 45 | 37.5 | Kansas State (KSU) | 17 | 17.0 | Iowa State (ISU) | 5 | 5 | 0 | |
| 18 | Kent State (KNT) | 14 | 14.0 | Bowling Green (BGU) | 11.5 | 24 | 12.5 | Kent State (KNT) | 2 | 0 | 2 | |
| 19 | Arkansas (ARK) | 5.5 | 10 | 4.5 | South Carolina (SCL) | 14 | 14.0 | South Carolina (SCL) | 7 | 2 | 5 | |
| 20 | Notre Dame (NDM) | 8.5 | 41 | 32.5 | Tennessee (TEN) | 21 | 21.0 | Notre Dame (NDM) | 22 | 16 | 6 | |
| 21 | UNLV (UNL) | 14 | 14.0 | BYU (BYU) | 11.5 | 55 | 43.5 | BYU (BYU) | 2 | 0 | 2 | |
| 22 | SMU (SMU) | 7.5 | 27 | 19.5 | Rice (RCE) | 7 | 7.0 | SMU (SMU) | 2 | 2 | 0 | |
| 23 | Utah (UTA) | 3 | 43 | 40.0 | Wyoming (WYO) | 13 | 13.0 | Utah (UTA) | 7 | 4 | 3 | |
| 24 | Utah State (UST) | 17 | 17.0 | Louisiana Tech (LTK) | 8 | 27 | 19.0 | Louisiana Tech (LTK) | 0 | 0 | 0 | |
| 25 | Boise State (BSU) | 35 | 56 | 21.0 | New Mexico State (NMS) | 6 | 6.0 | Boise State (BSU) | 3 | 3 | 0 | |
| 26 | Air Force (AIR) | 12.5 | 24 | 11.5 | Army (ARM) | 27 | 27.0 | Army (ARM) | 3 | 3 | 0 | |
| 27 | Ohio State (OSU) | 34 | 40 | 6.0 | Illinois (ILL) | 2 | 2.0 | Ohio State (OSU) | 2 | 2 | 0 | |
| 28 | Penn State (PSU) | 10.5 | 35 | 24.5 | Wisconsin (WIS) | 14 | 14.0 | Penn State (PSU) | 16 | 1 | 15 | |
| 29 | Mississippi St. (MST) | 0 | 0.0 | Alabama (ALA) | 17 | 17 | 0.0 | -1 | 3 | 1 | 2 | |
| 30 | Oregon (ORU) | 1 | 27 | 26.0 | California (CAL) | 20 | 20.0 | Oregon (ORU) | 12 | 10 | 2 | |
| 31 | Florida State (FSU) | 14 | 15 | 1.0 | N.C. State (NCS) | 20 | 20.0 | N.C. State (NCS) | 6 | 4 | 2 | |
| 32 | Washington (WAS) | 10 | 10.0 | Oregon State (ORS) | 4 | 18 | 14.0 | Oregon State (ORS) | 6 | 0 | 6 | |
| 33 | Colorado (COL) | 11.5 | 41 | 29.5 | Missouri (MIZ) | 12 | 12.0 | Colorado (COL) | 7 | 1 | 6 | |
| 34 | Troy State (TRO) | 3 | 28 | 25.0 | Florida International (FIU) | 14 | 14.0 | Troy State (TRO) | 2 | 2 | 0 | |
| 35 | Virginia (VIR) | 35 | 51 | 16.0 | Temple (TEM) | 3 | 3.0 | Virginia (VIR) | 4 | 3 | 1 | |
| 36 | Louisiana Monroe (LAM) | 11 | 29 | 18.0 | Florida Atlantic(FAU) | 31 | 31.0 | Florida Atlantic(FAU) | 0 | 0 | 0 | |
| 37 | Nevada (NEV) | 6.5 | 38 | 31.5 | Hawaii (HAW) | 28 | 28.0 | Nevada (NEV) | 4 | 4 | 0 | |
| 38 | Middle Tenn. St. (MTS) | 5.5 | 45 | 39.5 | Arkansas State (ARS) | 7 | 7.0 | Middle Tenn. St. (MTS) | 0 | 0 | 0 | |
| 39 | Washington State (WSU) | 24 | 24.0 | Arizona State (ASU) | 2.5 | 27 | 24.5 | Arizona State (ASU) | 6 | 0 | 6 | |
| 40 | Arizona (ARZ) | 52 | 52.0 | UCLA (UCL) | 8.5 | 14 | 5.5 | Arizona (ARZ) | 11 | 5 | 6 | |
| 41 | Central Florida (CFL) | 31 | 31.0 | Houston (HOU) | 3 | 29 | 26.0 | Central Florida (CFL) | 5 | 2 | 3 | |
| 42 | North Texas (NTX) | 28 | 28.0 | La Lafayette (LAL) | 3.5 | 31 | 27.5 | North Texas (NTX) | 1 | 0 | 1 | |
| 43 | TCU (TCU) | 6.5 | 33 | 26.5 | Colorado State (CSU) | 6 | 6.0 | TCU (TCU) | 6 | 6 | 0 | |
| 44 | Florida (FLA) | 19.5 | 49 | 29.5 | Vanderbilt (VAN) | 42 | 42.0 | Vanderbilt (VAN) | 7 | 4 | 3 | |
| 45 | Virginia Tech (VTK) | 6.5 | 7 | 0.5 | Miami Fla (MIF) | 27 | 27.0 | Miami Fla (MIF) | 9 | 2 | 7 | |
| 46 | Fresno State (FST) | 33 | 45 | 12.0 | San Jose State (SJS) | 7 | 7.0 | Fresno State (FST) | 2 | 2 | 0 | |
| 47 | UTEP (UTP) | 8 | 41 | 33.0 | Tulsa (TLS) | 38 | 38.0 | Tulsa (TLS) | 5 | 4 | 1 | |
| 48 | USC (USC) | 32.5 | 51 | 18.5 | Stanford (STN) | 21 | 21.0 | Stanford (STN) | 13 | 7 | 6 |